Juvederm/Juvederm XC
The new JUVÉDERM® XC formulation is enhanced for patient comfort. You can now get the smoothness you expect, with the improved comfort you want ‡. JUVÉDERM® XC provides smooth and natural looking results and now a more comfortable experience – so everyone will notice but no one will know! In fact, studies show results of JUVÉDERM® last up to one year.**
Over 90% of subjects reported less treatment pain with JUVÉDERM® XC compared to non-lidocaine Juvederm.

JUVÉDERM® is a smooth consistency gel made of hyaluronic acid – a naturally occurring substance in your skin that helps to add volume and hydration. Your healthcare professional eases JUVÉDERM® injectable gel under the skin to instantly restore your skin's volume and smooth away facial wrinkles and folds, like your “smile lines” or “parentheses” (nasolabial folds – the creases that run from the bottom of your nose to the corners of your mouth).
• JUVÉDERM® provides smooth and natural looking results.
• JUVÉDERM® is the only hyaluronic acid (HA) filler FDA
approved* to last up to 1 year.
• JUVÉDERM® New JUVÉDERM® XC is now formulated with an anesthetic for a
more comfortable patient experience.‡
With JUVÉDERM® the injection process takes only about 15 minutes and results are immediate. Plus, there’s minimal recovery or downtime. So you can step into your doctor’s office for treatment and step right back into your life. And now with the newest formulation of JUVÉDERM®, the effects of lidocaine take place in seconds, potentially reducing the need for further anesthetic.†
With JUVÉDERM® or JUVÉDERM® XC you should see an immediate improvement in the treatment areas. Most patients need one treatment to achieve optimal wrinkle smoothing. And one treatment could smooth your lines and wrinkles for up to 1 year. However, results may vary and correction is temporary. Supplemental “touch up” treatments may be required to achieve and maintain optimal results.
What to expect during treatment
Before you go: Some doctors recommend that you avoid any medications that can prolong bleeding, such as aspirin and non-steroidal anti-inflammatories (NSAIDs), for at least a week prior to treatment in order to reduce the risk of bruising and bleeding at the injection site. Ask your doctor what he or she recommends.
Determining your treatment needs: Your doctor will examine the soft tissue of your face to assess the depth of wrinkles and folds to determine your treatment. They may even take pre-treatment photographs so you can see the difference after treatment!
Before the procedure: Although anesthesia is not required, topical or injectable anesthesia may be used to numb the treatment area first.
The procedure: Your doctor will ease the JUVÉDERM® injectable gel under your skin to augment, or fill, wrinkles and folds. Following the injection, your healthcare professional may gently massage the treated areas. The procedure is quick and easy. The injection itself usually takes only about 15 minutes.
After the procedure: With JUVÉDERM®, there is minimal recovery or downtime.
For the first 24 hours following treatment, you should avoid strenuous exercise, excessive sun or heat exposure, and consumption of alcoholic beverages in order to help minimize the risks of temporary redness, swelling, and/or itching at the treatment sites. After the treatment, some temporary injection-related reactions may occur, including redness, pain, firmness, swelling, and bumps. Studies have shown that these are usually mild to moderate in nature and clear up on their own in 7 days or less. If you experience swelling at the injection site, you can apply an ice pack for a brief period. Your doctor will tell you when makeup may be applied after your treatment.
Important JUVÉDERM® Safety Information
JUVÉDERM® injectable gel (including JUVÉDERM® Ultra, JUVÉDERM® Ultra Plus, JUVÉDERM® Ultra XC, and JUVÉDERM® Ultra Plus XC) is indicated for correction of moderate to severe facial wrinkles and folds (such as nasolabial folds). Side effects were usually mild to moderate, lasting 7 days or less, and included temporary injection-site reactions such as redness, pain, firmness, swelling, and bumps. JUVÉDERM® is not for people with severe allergies. For more information, please click on the About Safety link at www.juvederm.com or call the Allergan Product Support line at 1-877-345-5372. JUVÉDERM® injectable gel is available by prescription only.
*In the United States, JUVÉDERM® injectable gel is indicated for injection into the mid to deep dermis for correction of moderate to severe facial wrinkles and folds (such as nasolabial folds).
**Pinsky MA, Thomas JA, Murphy DK, Walker PS; for JUVÉDERM® vs. ZYPLAST® Nasolabial Fold Study Group. Juvederm injectable gel: A multicenter, double-blind, randomized study of safety and effectiveness. Aesthetic Surg J. 2008:28(1):17-23.
‡Compared to the non-lidocaine JUVÉDERM® formulation.
†Data on file, Allergan, Inc.; Weinkle SH, Bank DE, Boyd CM, Gold MH, Thomas JA, Murphy DK. A multi-center, double-blind, randomized controlled study of the safety and effectiveness of JUVÉDERM® injectable gel with and without lidocaine. J Cosmet Dermatol. 2009;8(3):205-210. Please see JUVÉDERM® Ultra XC and JUVÉDERM® Ultra Plus XC Patient Safety Information for more information.
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